Equine Laminitis

Contributors

Foreword

Abbreviations

Part 1: Overview: From Basic Research to Caring for the Laminitis Patient

1 Historical Perspective on Equine Laminitis

2 Laminitis: An Overview

3 Anatomy and Function of the Equine Digit

4 Lamellar Function at the Cellular Level

5 Digital Biomechanics Relevant to Laminitis

Part 2: Pathophysiology of Laminitis

6 Overview

7 Experimental Models of Laminitis: Starch Overload

8 Experimental Models of Laminitis: Oligofructose Overload

9 Experimental Models of Laminitis: BlackWalnut Extract

10 Experimental Models of Laminitis: Hyperinsulinemia

11 Hemodynamic Events in Laminitis

12 The Role of Thrombosis and Coagulation in Equine Laminitis

13 Leukocytes and Inflammatory Signaling in Laminitis: Leukocytes

14 Leukocytes and Inflammatory Signaling in Laminitis: Inflammatory Signaling

15 Role of Proteases in Laminitis

16 Endocrine and Metabolic Dysregulation in Laminitis: Role of Pituitary Dysfunction

17 Endocrine and Metabolic Dysregulation in Laminitis: Role of Corticosteroids

18 Metabolic Syndrome in Humans and Horses: The Relationship Between Obesity and Insulin Resistance

19 Dysregulation of the Lamellar Basal Epithelial Cell in Laminitis: Role of the Cytoskeleton and Cell Junctions

20 Structural Dynamics of Displacement of the Distal Phalanx

Part 3: Clinical Presentation of Equine Laminitis

21 General Clinical Aspects of the Laminitis Case

22 Sepsis-Related Laminitis

23 Laminitis in Equine Metabolic Syndrome

24 Laminitis in Pituitary Pars Intermedia Dysfunction

25 Supporting Limb Laminitis

Part 4: Diagnostic Evaluation of Equine Laminitis

26 Detailed Physical Examination for Laminitis

27 Diagnostic Imaging

28 The Digital Venogram

29 Endocrine and Metabolic Evaluation in Horses with Laminitis

Part 5: Medical Treatment of the Laminitic Patient

30 General Supportive Care for the Laminitis Case

31 Common Therapies: Anti-Inflammatory Therapy

32 Vasoactive Drug Therapy

33 Analgesia

34 Digital Hypothermia

35 Equine Sepsis

36 Equine Metabolic Syndrome

37 Pituitary Pars Intermedia Dysfunction

Part 6: Treatment of Laminitis: Digital Support and Stabilization of the Distal Phalanx

38 Therapeutic Shoes: Application of Principles

39 Solear Support Techniques

40 Approaching Digital Management Prior to Displacement of the Distal Phalanx

41 Hoof Care Management of Horses with Displacement of the Distal Phalanx

Part 7: Treatment of the Laminitis Case

42 The Use of Casts in Equine Laminitis

43 Deep Digital Flexor Tenotomy

44 Dorsal HoofWall Techniques

45 Complications of Laminitis

Part 8: Management of Chronic Laminitis

46 Management Changes in the Laminitis Case

Part 9: Prevention of Laminitis

47 Overview of Laminitis Prevention

48 Prevention of Supporting Limb Laminitis

49 Prevention of Sepsis-Related Laminitis

50 Nutritional Management for Avoidance of Pasture-Associated Laminitis

Glossary

Index