Lactogenic immunity in the sow
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Lactogenic immunity in the sow

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Good transfer of passive immunity from sows to piglets is crucial to ensure piglet survival on pig farms. This book is intended to help veterinary practitioners work towards this goal, and includes a review of the basics of immunology and vaccination, as well as comprehensive chapters on the immunisation programmes used in sows and on the transfer of passive immunity from sows to piglets.

Lorenzo José Fraile Sauce

Degree in Veterinary Medicine (1992) and Doctor of Veterinary Pharmacology in 1996, both from the University of Zaragoza, Spain, then specialist pig vet for Cargill España S.A. and Picber S.A. until 2004.

Researcher at the Centre de Recerca en Sanitat Animal (CReSA; Centre for Animal Health Research) from 2004 to 2010, where he was head of the Department of Epidemiology, Disease Control and Clinical Trials. Collaborator with the European Medicines Agency from 2005 to 2007, assessing veterinary medicines submitted for registration in Europe through his work on the Committee for Medicinal Products for Veterinary Use (CVMP). Member of the Scientific Advice Group on Antimicrobials, which provides scientific advice on all aspects of the use of antimicrobials in veterinary medicine to CVMP, from 2006 to 2007.

Adjunct professor of Epidemiology and Pharmacology at the University of Lleida since 2010, and involved in teaching the Masters Degree in Swine Production and Health offered by the Complutense University of Madrid, the University of Lleida and the University of Zaragoza. His current fields of scientific interest are epidemiology, immunology and clinical pharmacology, and his research aims to optimise preventative medicine programmes in pigs. He is the author of over 80 articles published in international scientific journals and 130 papers presented at national and international conferences. Finally, he has been a speaker at many veterinary conventions.

1. Introduction

Basic immunological concepts

Innate immunity

Cellular component

Humoral component

Adaptive (acquired) immunity

Humoral component

Cellular component

Dynamics of the immune response

Relative importance of cellular and humoral immunity in effective protection

2. General principles of vaccines and vaccination


Methods of active artificial immunisation

Practical vaccine application

Adverse reactions to vaccines

3. Transfer of passive immunity to the piglet

Passive immunity and its role in the piglet


Colostrum, transient milk and mature milk

The role of colostrum in newborn piglet survival

Transfer of humoral and cellular immunity


Humoral immunity

Cellular immunity

Strategy for improving the transfer of passive immunity

Interference with active immunity by passive immunity


Interference with the development of humoral immunity

Interference with the development of cellular immunity

Strategies to overcome maternal immunity and develop effective active immunity in the newborn

4. Prevention programmes in pigs

Basic concepts

Bacterial diseases: sow vaccination programmes

Vaccination against exotoxin–producing bacteria

Vaccination against extracellular bacteria

Viral diseases: sow vaccination programmes

Vaccination against porcine reproductive and respiratory syndrome

Vaccination against porcine circovirus disease

Vaccination against parvovirus infection

Vaccination against swine influenza

5. Practical aspects of the transfer of passive immunity to the piglet

Management of colostrum consumption1

Factors related to quality

Factors related to quantity

Measuring the transfer of passive immunity


  • Autor/es Lorenzo José Fraile Sauce
  • Fecha de edición abril 2018
  • Nº Páginas 144
  • Encuadernación Tapa dura
  • Tamaño 17 X 24
  • Idioma Inglés

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